Modelling of filamentous phage-induced antibiotic tolerance of P.aeruginosa

55 Likes, 13 Comments - UCLA VA Physiatry Residency (@uclava_pmrresidency) on Instagram: “Resident’s Corner: Name: David Huy Blumeyer, MD Year in residency: PGY-4 Where were you born…” In recent decades, the frequent and irregular use of antibiotics has caused the problem of bacterial resistance to become a public health crisis , , , , , .According to the latest investigation by the Centers for Disease Control and Prevention (CDC), antibiotic resistance causes millions of illnesses around the world every year, it is estimated that by 2050, the number of deaths due to ... P. aeruginosa, another common gram ... called “persister cells,” are dormant variants that exhibit antibiotic tolerance and can become active when the therapy is withdrawn [1, 8, 32, ... Bacteriophages including filamentous phage particles help in releasing eDNA and the development of antibiotic tolerant colonies within biofilms . 8. Introduction. Plants are colonized by an astounding number of (micro)organisms that can reach cell densities much greater than the number of plant cells (Fig. 1).Also, the number of microbial genes in the rhizosphere outnumbers by far the number of plant genes (Fig. 1).An overwhelming number of studies have revealed that many plant-associated microorganisms can have profound effects on seed ... In P. aeruginosa biofilms eDNA forms a grid-like structure 70, whereas in an aquatic bacterial isolate (a gammaproteobacterium called strain F8) eDNA forms a filamentous network 71 . In cocultures with DSF-producing S. maltophilia and P. aeruginosa, the biofilm of P. aeruginosa changed from a flat to a filamentous biofilm. A filamentous biofilm was also observed in monocultures of P. aeruginosa supplemented with 10 or 50 μM DSF. The PA1396 protein of P. aeruginosa was identified as a two-component sensor of DSF .

2021.12.04 05:11 sburgess86 Modelling of filamentous phage-induced antibiotic tolerance of P.aeruginosa

Modelling of filamentous phage-induced antibiotic tolerance of P.aeruginosa submitted by sburgess86 to BiologyPreprints [link] [comments]

2021.12.04 05:11 derNamederHose Chair for sitting + deep squat ??

Hey guys, I need a new office chair and was wondering if there is something that also allows you to sit in the deep squat? To my surprise, I can't find anything. Thanks!
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2021.12.04 05:11 ninja-fapper [Gift Card][Walmart] $200 Apple Gift Card - $143.09

[Gift Card][Walmart] $200 Apple Gift Card - $143.09 submitted by ninja-fapper to gachagaming [link] [comments]

2021.12.04 05:11 Feenix47 My recent hiring process experience

I just received closure to a complete clusterfuck I have never experienced previously in my professional career. I thought I’d share here and see what everyone’s opinions are on whether I’m an idiot or if I dodged a ballistic nuclear missile.
On October 15th of this year, a recruiter from a European Fintech reached out to me on LinkedIn because my experience matched with a role she was recruiting for. I agreed to a phone interview and we spoke for around half an hour. She then stated to expect an invite to take an assessment within 48 hours. I did not hear back from her for 11 days.
On October 26th, I received a message from her apologizing for the delay as she was on leave. I’m sorry but why the fuck would you begin the hiring process for a potential candidate for a crucial senior role and then go on vacation for 10 days without notifying said candidate.
Anyways, she sends me the assessment and turns out to be a silly test on basic math and pattern recognition with a completely useless personality test at the end. After completing this test, I received a response on November 4th asking for when it would be a good time to talk to their CRO. Interview was set for November 11th. On the 11th, I hop on the call to come to learn that the CRO got pulled away last minute and I’d speaking to someone else. Ok fine whatever shit happens. Interview goes well, lasts the complete duration with the interviewer letting me know that they would be definitely following up for the final interview. On November 19th I get an interview request for the final interview to meet with someone on November 24th, the day before Thanksgiving.
On November 24th, I had my final interview where i spent 20 minutes explaining my thought process regarding a hypothetical business case. After that, we spoke for an additional 20 minutes regarding any questions the interviewer or myself had. Afterwards, the gentleman informed me I’d be receiving an answer by Friday. I said sounds good and went back to prepped for Thanksgiving Dinner. This is where it gets fucky-fucky.
On November 26th, I receive an email from a completely different recruiter from the same company, trying to recruit me for a position I had never heard of nor had any interest in. She was trying to set up a final interview with myself and some senior leader. I was like wtf is this person high or just stupid? I respond stating that there must be a mistake or confusion somewhere as I am currently in the hiring process for a different position. I CCed the recruiter I had been dealing with from the start hoping for a swift remedy. BOY WAS I WRONG.
I received a response on 11/29 from Recruiter #2 apologizing for the confusion and that I wouldn’t have to have another interview and I quote “so we won’t be able to proceed with either and I apologize”. I had no idea what she meant by that so I responded asking for further clarification and reached out to the first recruiter asking for assistance. On 12/1, the position I was up for was reposted on LinkedIn and I finally received a response an hour ago from the first recruiter telling me to get bent. But here’s the kicker, the position in the subject email was for the same role recruiter #2 reached out to me for.
Never have I ever had such a horrendous experience like this in my professional career. This organization is one I have dealt with in my current position several times in the past and I never had any experience remotely similar to this shit-show. The fucked up thing is, I really wanted this job and knew I’d kill it so for this to happen is pretty gut wrenching.
Oh well.
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2021.12.04 05:11 dasun0218 Japanese Bird That Looks Like A Flying Cotton Flower

Japanese Bird That Looks Like A Flying Cotton Flower submitted by dasun0218 to aww [link] [comments]

2021.12.04 05:11 Mecha_dad33 I'll be seeing that Acguy in my nightmares... (Full armor Slave Wraith gameplay)

I'll be seeing that Acguy in my nightmares... (Full armor Slave Wraith gameplay) submitted by Mecha_dad33 to GBO2 [link] [comments]

2021.12.04 05:11 Master_Paramedic_472 هووووووی به ایتن بی احترامی نکن

هووووووی به ایتن بی احترامی نکن submitted by Master_Paramedic_472 to keoXer [link] [comments]

2021.12.04 05:11 Squirrel_Lionfart Cintiq 27QHD, Stand Alternatives Ideas

Hey, it’s the guy with all the 27QHD questions, who finally started using reddit. So I decided to keep my Cintiq 27QHD, because I find the 1440p resolution and the colour gamut amazing. But I really wanna see for other options to have it in my desk. Something much lighter than the cintiq stand (ridiculously overpriced and heavy) and get rid of my Ergotron Arm (heavy, bulky, covers the cable tray). I need some good tips, for alternatives. Maybe the newer simple Wacom stand that comes with the new Cintiq 22, could hold the big heavy 27QHD? Would love to find such a practical minimalistic stand for it. Easier to store and transport and change angles. That Ergotron arm seems like it could break off the back part of my Cintiq, when i move it back and forth… not good.
Thanks in advance for any ideas, experiences and tips. Cheers!
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2021.12.04 05:11 Jasminella_217 Can't hold laugh anymore. HAHA

Can't hold laugh anymore. HAHA submitted by Jasminella_217 to SubscribeToMe [link] [comments]

2021.12.04 05:11 ickyvicky669 Suggestions??:/

Please delete if not allowed, but I feel like I am so clingy I have taken time for myself and have tried. He feels so much like a safe spot but recently we’ve just been so bad and it’s bothering us both. I had to go to my grandparents & he stayed at his dads. I have so many issues and I don’t want to push them on him although he tries to. I feel like he wasn’t his self for the last three days like I couldn’t do anything. How can I be too much and not enough?? I’m going to therapy to help myself, I just wish I knew what to do and how to make him happy.
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2021.12.04 05:11 Booperlol [Request][USA] Postcards for my girlfriend's birthday

Hello everyone! My girlfriend's birthday is coming up this December and I thought it would be lovely if any of you guys could surprise her with some postcards. She has a hobby of collecting postcards and anything you can send will be much appreciated. As a December baby, her birthday is sometimes forgotten since it is so close to Christmas. It would be amazing if I could just bring a smile to her face. She loves playing Animal Crossing, Sims, and collecting Lego minifigure series! She is also a big movie person if you would like to mention your favorite movie. Thank you! :)
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2021.12.04 05:11 sburgess86 Plug and play: Is "directed endosymbiosis" of chloroplasts possible?

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2021.12.04 05:11 Krblshna You better run from this one (Lord Ambermaze)

You better run from this one (Lord Ambermaze) submitted by Krblshna to IndieDev [link] [comments]

2021.12.04 05:11 throwaway1234567ay I(F21) don’t like my boyfriend’s(M21) mom

We’ve been dating for 7 months so far, and I did like her in the beginning. As I started coming over more and as my boyfriend and I started getting closer, I started to realize his mom has some major flaws (…in my eyes?).
There’ve been multiple occasions where I’d find my boyfriend or my boyfriend would tell me how lost and depressed he is because his financial situation. He has a good paying job, but a shit car (he got from his parents) that has horrible gas mileage, is very old, and already broke down multiple times.
His mom is so stingy with her money, and will never stop giving him a hard time or giving him the stink face if he asks for $20 for gas once a month because he NEEDS it. She gets mad at him when he asks to borrow some money and brings up how he makes more than her… He literally makes 25 cents more than her….
She doesn’t have to pay gas herself because she carpools everywhere with his dad. The only thing she pays for is the lease on her Audi that she was never able to afford and never uses, and her luxury bags that pops through the door once a month.
I and his dad always helped him out when he needed it the most. There’s been multiple times I’ve found him sitting on the edge of his bed with a lost look on his face, because his mom would never help him out and left him high and dry because she was stingy with her money.
I will never speak on this with my boyfriend, but I will never respect his mother for the way she is.
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2021.12.04 05:11 Killinthagame How I feel about my investment in SFM

How I feel about my investment in SFM submitted by Killinthagame to SafeMoonInvesting [link] [comments]

2021.12.04 05:11 ContentForager2 ¿Me van a decir que no sería hermoso que existiera? (/r/chile)

¿Me van a decir que no sería hermoso que existiera? (/chile) submitted by ContentForager2 to mistyfront [link] [comments]

2021.12.04 05:11 readerseven Nissan unveils prototype lunar exploration vehicle

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2021.12.04 05:11 JupiterWolf99love My crimped Eevee Vmax promo!

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2021.12.04 05:11 sburgess86 Age-related decline in function of ON and OFF visual pathways

Age-related decline in function of ON and OFF visual pathways submitted by sburgess86 to BiologyPreprints [link] [comments]

2021.12.04 05:11 LoudGangsta8292 What blaster is this?

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2021.12.04 05:11 nobrakes1975 Back to the nativity, ink drawing by me, 2021.

Back to the nativity, ink drawing by me, 2021. submitted by nobrakes1975 to delorean [link] [comments]

2021.12.04 05:11 Zaphkiel_Mei [VTubersPage] Congrats to Sakamata Chloe For Becoming the First HoloX Member to REACH 500,000 SUBSCRIBERS in 4 DAYS And Also Breaking the Record for FASTEST VTUBER TO REACH THIS MILESTONE

[VTubersPage] Congrats to Sakamata Chloe For Becoming the First HoloX Member to REACH 500,000 SUBSCRIBERS in 4 DAYS And Also Breaking the Record for FASTEST VTUBER TO REACH THIS MILESTONE submitted by Zaphkiel_Mei to Hololive [link] [comments]

2021.12.04 05:11 Little_DimbXD Meme for every Hero, enjoy

Meme for every Hero, enjoy submitted by Little_DimbXD to ClashMini [link] [comments]

2021.12.04 05:11 Pinkchips4837 Experience with upping to 60mg?

I’ve been on 40mg for about 2 months and while it’s been good, there’s still some lingering ocd thoughts and anxiety, which has recently got a bit worse. What have your experiences been upping from 40mg to 60? Does it kick the last of the anxiety?
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2021.12.04 05:11 budyll66 Why so many things in the UK have to be different to the rest of the world?

Hi people,
I've lived in England for the past 11yrs and I've always been curious about certain aspects of things in here. I've got a few questions regarding day to day life. Here goes (don't get offended people :P) : 1. Why do we have to drive on the left side of the road and right? 2. Why most of the population here doesn't know how do kilograms work and who came up with an idea of "stones"? No stone is equal so I'll never got it. 3. Why "Lays" crisps are called "Walkers" here? 4. Why Opel cars are called Vauxhall?
That's pretty much everything I could think about right now. Just to add, this post is by no means meant to offend anyone, I was simply wondering about the above for years and finally decided to ask about it.
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